Sialyl-Lewis X

CAT: 0931-T35884-01Size: 1 mgDry Ice: NoHazardous: No

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CAT#:0931-T35884-01Size:1 mg

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CAS Number

98603-84-0

Target

Others, Endogenous Metabolite

Related Pathways

Others, Metabolism

Bioactivity

Sialyl-Lewis X (sLeX), a sialylated fucosylated tetrasaccharide and endogenous antigen, serves as a high-affinity ligand for selectins (E-, P-, and L-selectin) [1]. It interacts with ELAM-1 and CD62, consequently inhibiting CD62-mediated neutrophil recruitment to inflammation sites[2].

Smiles

[H][C@]1(O[C@@](C[C@H](O)[C@H]1NC(C)=O)(O[C@H]1[C@@H](O)[C@@H](CO)O[C@@H](O[C@H]([C@H](O)CO)[C@H](O[C@@H]2O[C@@H](C)[C@@H](O)[C@@H](O)[C@@H]2O)[C@@H](NC(C)=O)C=O)[C@@H]1O)C(O)=O)[C@H](O)[C@H](O)CO

Molecular Formula

C31H52N2O23

Molecular Weight

820.748

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Chemical Information

Sialyl Lewis X Antigen

A sialylated version of Lewis X antigen expressed on cell surfaces. It is a ligand for SELECTINS.

CAS Number	98603-84-0
PubChem CID	643990
IUPAC Name	(2S,4S,5R,6R)-5-acetamido-2-[(2S,3R,4S,5S,6R)-2-[(2R,3R,4R,5R)-5-acetamido-1,2-dihydroxy-6-oxo-4-[(2S,3S,4R,5S,6S)-3,4,5-trihydroxy-6-methyloxan-2-yl]oxyhexan-3-yl]oxy-3,5-dihydroxy-6-(hydroxymethyl)oxan-4-yl]oxy-4-hydroxy-6-[(1R,2R)-1,2,3-trihydroxypropyl]oxane-2-carboxylic acid
Molecular Formula	C31H52N2O23
Molecular Weight	820.7
XLogP	-8.6
Topological Polar Surface Area	411
Hydrogen Bond Donor Count	15
Hydrogen Bond Acceptor Count	23
Rotatable Bond Count	18
Heavy Atom Count	56
Formal Charge	0
Complexity	1320

SMILES

C[C@H]1[C@H]([C@H]([C@@H]([C@@H](O1)O[C@H]([C@H](C=O)NC(=O)C)[C@@H]([C@@H](CO)O)O[C@H]2[C@@H]([C@H]([C@H]([C@H](O2)CO)O)O[C@@]3(C[C@@H]([C@H]([C@@H](O3)[C@@H]([C@@H](CO)O)O)NC(=O)C)O)C(=O)O)O)O)O)O

InChI

InChI=1S/C31H52N2O23/c1-9-18(43)21(46)22(47)28(51-9)53-24(12(5-34)32-10(2)38)25(15(42)7-36)54-29-23(48)27(20(45)16(8-37)52-29)56-31(30(49)50)4-13(40)17(33-11(3)39)26(55-31)19(44)14(41)6-35/h5,9,12-29,35-37,40-48H,4,6-8H2,1-3H3,(H,32,38)(H,33,39)(H,49,50)/t9-,12-,13-,14+,15+,16+,17+,18+,19+,20-,21+,22-,23+,24+,25+,26+,27-,28-,29-,31-/m0/s1

InChIKey

LAQPKDLYOBZWBT-NYLDSJSYSA-N

Chemical Structure

2D Structure

CAS: 98603-84-0

CID: 643990

Formula: C31H52N2O23

MW: 820.7

Interactive 3D Structure

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View on PubChem Raw 3D data

Computed Properties

Property	Value
Molecular Weight	820.7
XLogP3	-8.6
Hydrogen Bond Donor Count	15
Hydrogen Bond Acceptor Count	23
Rotatable Bond Count	18
Exact Mass	820.29608591
Monoisotopic Mass	820.29608591
Topological Polar Surface Area	411 Å²
Heavy Atom Count	56
Formal Charge	0
Complexity	1320
Isotope Atom Count	0
Defined Atom Stereocenter Count	20
Undefined Atom Stereocenter Count	0
Defined Bond Stereocenter Count	0
Undefined Bond Stereocenter Count	0
Covalently-Bonded Unit Count	1
Compound Is Canonicalized	Yes

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TSW-00775-01	Lewis-b tetrasaccharide
TSW-00523-01	3′-Sialyl-N-acetyllactosamine
TN9901-01	Cytorhodin X
TN2369	Tenacissoside X
T3S0289	Araloside X
T19075-01	X-GAL

Alternative Products

Catalog	Name
253961	CA19-9 (Sialyl Lewis (a), Sialyl Lewis (a), Sialyl Lewisa)
56/51-0001	Sialyl-Lewis a
HY-W854385	Sialyl Lewis A
GWB-D3226C	Sialyl Lewis a Antibody
MBS5784953	Sialyl-Lewis X
sc-51696	Sialyl Lewis a (121SLE)
S1013-51B-01	Sialyl Lewis X
C00173-1mg*5	Anti-Sialyl-Lewis A
OS00745-01	3'-Sialyl Lewis A
GTR19274995-01	Sialyl Lewis A sodium

Sialyl-Lewis X

Chemical Information

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