Mitoguazone

• Target :

  Apoptosis|||HIV Protease

• Related Pathways :

  Apoptosis|||Microbiology/Virology|||Proteases/Proteasome

• Purity :

  0.98

• Bioactivity :

  Mitoguazone (Methyl-GAG) is a selective S-adenosyl-methionine decarboxylase inhibitor that penetrates the blood-brain barrier and disrupts polyamine biosynthesis. Mitoguazone is a synthetic polycarbonyl derivative with anti-tumor activity that inhibits the integration of HIV DNA into cellular DNA in monocytes and macrophages, inducing apoptosis. Mitoguazone can be used to prevent acute leukemia, Hodgkin lymphoma and non-Hodgkin lymphoma.

• Smiles :

  C\C(\C=N\NC(N)=N)=N/NC(N)=N

• Molecular Formula :

  C5H12N8

• Molecular Weight :

  184.2

• Shipping Conditions :

  Cool pack

• Storage Temperature :

  -20°C

• CAS Number :

  459-86-9