OAB-14

• Target :

  Others|||Beta Amyloid

• Related Pathways :

  Others|||Neuroscience

• Bioactivity :

  OAB-14 is a Bexarotene derivative that improves Alzheimer's disease-related pathologies and cognitive impairments by increasing ?-amyloid clearance in APP/PS1 mice. OAB-14 effectively ameliorates the dysfunction of the endosomal-autophagic-lysosomal (EAL) pathway in APP/PS1 transgenic mice [1] [2].

• Smiles :

  CC1(C)CCC(C)(C)c2c(NC(=O)c3ccc(NC(=O)NCCN)cc3)c3c(cc12)C(C)(C)CCC3(C)C

• Molecular Formula :

  C32H46N4O2

• Molecular Weight :

  518.73

• Shipping Conditions :

  Cool pack

• Storage Temperature :

  -20°C

• CAS Number :

  2140911-49-3