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OAB-14

CAT: 0931-T33766-01Size: 25 mgDry Ice: NoHazardous: No
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CAT#:0931-T33766-01Size:25 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
2140911-49-3
Target
Others, Beta Amyloid
Related Pathways
Others, Neuroscience
Bioactivity
OAB-14 is a Bexarotene derivative that improves Alzheimer's disease-related pathologies and cognitive impairments by increasing β-amyloid clearance in APP/PS1 mice. OAB-14 effectively ameliorates the dysfunction of the endosomal-autophagic-lysosomal (EAL) pathway in APP/PS1 transgenic mice [1] [2].
Smiles
CC1(C)CCC(C)(C)c2c(NC(=O)c3ccc(NC(=O)NCCN)cc3)c3c(cc12)C(C)(C)CCC3(C)C
Molecular Formula
C32H46N4O2
Molecular Weight
518.73
Shipping Conditions
Ice Packs
Storage Temperature
-20°C