OAB-14

• Target:

  Others|||Beta Amyloid

• Related Pathways:

  Others|||Neuroscience

• Bioactivity:

  OAB-14 is a Bexarotene derivative that improves Alzheimer's disease-related pathologies and cognitive impairments by increasing ?-amyloid clearance in APP/PS1 mice. OAB-14 effectively ameliorates the dysfunction of the endosomal-autophagic-lysosomal (EAL) pathway in APP/PS1 transgenic mice [1] [2].

• Smiles:

  CC1 (C) CCC (C) (C) c2c (NC (=O) c3ccc (NC (=O) NCCN) cc3) c3c (cc12) C (C) (C) CCC3 (C) C

• Molecular Formula:

  C32H46N4O2

• Molecular Weight:

  518.73

• Shipping Conditions:

  Cool pack

• Storage Temperature:

  -20°C

• CAS Number:

  2140911-49-3