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DBRD9

CAT: 0931-T31221-01Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0931-T31221-01Size:1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
2170679-45-3
Target
PROTACs, Epigenetic Reader Domain
Related Pathways
PROTAC, Chromatin/Epigenetic
Purity
0.9981
Bioactivity
DBRD9 is a PROTAC. dBRD9 is a double-acting molecule, partially containing Bromodomain-containing protein 9 (BRD9), ligand that recruits the cereblon E3 ubiquitin ligase. Ligand that recruits the cereblon E3 ubiquitin ligase. dBRD9 can inhibit the degradation of BRD9 in MOLM-13 cells, and the IC50 is 104 nM.
Smiles
O=C1C=2C(C(=O)N1C3C(=O)NC(=O)CC3)=CC=CC2NCCOCCOCCNC(CN(CC4=C(OC)C=C(C=C4OC)C=5C=6C(C(=O)N(C)C5)=CN=CC6)C)=O
Molecular Formula
C40H45N7O10
Molecular Weight
783.83
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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