Products for Research Use Only

CGP77675 hydrate

CAT: 0931-T30855L-01Size: 25 mgDry Ice: NoHazardous: No
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CAT#:0931-T30855L-01Size:25 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Target
Src, Others
Related Pathways
Angiogenesis, Tyrosine Kinase/Adaptors, Others
Bioactivity
CGP77675 hydrate is an orally active, potent inhibitor of Src family kinases. It inhibits the phosphorylation of peptide substrates and autophosphorylation of purified Src (IC50: 5-20 and 40 nM, respectively), as well as Src, EGFR, KDR, v-Abl, and Lck with IC50s of 0.02, 0.15, 1.0, 0.31, and 0.29 μM, respectively. CGP77675 hydrate may be useful for treating diseases associated with elevated bone loss and has anticancer activity [1].
Shipping Conditions
Ice Packs
Storage Temperature
-20°C