Products for Research Use Only

CGP77675

CAT: 0013-GTR19171478-01Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19171478-01Size:1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
CGP77675 (ZINC1488120) is a potent, selective Src family kinase inhibitor, demonstrating IC50 values of 5-20 nM for peptide substrate phosphorylation and 40 nM for Src autophosphorylation. Its anticancer activity supports its use in vitro and in vivo for researching cancer cell signaling, proliferation, and metastasis.
CAS Number
234772-64-6
Product Name Alternative
ZINC 1488120, ZINC1488120, ZINC-1488120, Src, v-Abl, EGFR, Lck, KDR, BcrAbl, 1- (4- (4-amino-5- (3-methoxyphenyl) -7H-pyrrolo[2,3-d]pyrimidin-7-yl) phenethyl) piperidin-4-ol, CGP77675, CGP-77675, CGP 77675
Field of Research
Cardiovascular Research, Signal Transduction
Purity
98.23% (May vary between batches)
Solubility
DMSO:55 mg/mL (124 mM) ;10% DMSO+90% Saline:2.5 mg/mL (5.64 mM)
Smiles
NC1=C2C (=CN (C2=NC=N1) C3=CC=C (CCN4CCC (O) CC4) C=C3) C5=CC (OC) =CC=C5
Molecular Formula
C26H29N5O2
Molecular Weight
443.54
Storage Conditions
-20°C
Notes
For research use only.