Edonentan hydrate

• Target:

  Endothelin Receptor

• Related Pathways:

  GPCR/G Protein

• Bioactivity:

  Edonentan (BMS 207940) hydrate effectively blocks the endothelin A (ETA) receptor as a potent and selective antagonist, featuring a K i of 10 pM. It exhibits complete (100%) oral bioavailability in rats [1].

• Smiles:

  C(N(C(CC(C)(C)C)=O)C)C1=C(C=CC(=C1)C2=NC=CO2)C3=C(S(NC=4C(C)=C(C)ON4)(=O)=O)C=CC=C3.O

• Molecular Formula:

  C28H34N4O6S

• Molecular Weight:

  554.66

• Shipping Conditions:

  Cool pack

• Storage Temperature:

  -20°C

• CAS Number:

  264609-13-4