BMS-695735

• Target :

  Others|||IGF-1R

• Related Pathways :

  Tyrosine Kinase/Adaptors|||Others

• Bioactivity :

  BMS-695735, a benzimidazole inhibitor of insulin-like growth factor-1 receptor, has broad-spectrum antitumor activity in vivo. It was found that BMS-695735 had strong inhibition of CYP3A4, induction of CYP3A4 mediated by PXR transactivation, poor water solubility, and high plasma protein binding.

• Smiles :

  N(CCN1C=C(Cl)C=N1)C2=C(C=3NC=4C(N3)=C(C)C=C(C4)C5CCN(CCCF)CC5)C(=O)NC=C2

• Molecular Formula :

  C26H31ClFN7O

• Molecular Weight :

  512.02

• Shipping Conditions :

  Cool pack

• Storage Temperature :

  -20°C

• CAS Number :

  1054315-48-8