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Thaspine acetate

CAT: 0931-T28960-01Size: 25 mgDry Ice: NoHazardous: No
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CAT#:0931-T28960-01Size:25 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
74578-01-1
Target
Others, Cytochromes P450, Bcl-2 Family, Apoptosis, Topoisomerase
Related Pathways
DNA Damage/DNA Repair, Apoptosis, Others, Metabolism
Bioactivity
Thaspine acetate is a potent topoisomerase IB inhibitor. Taspine downregulates VEGF expression and inhibits proliferation of vascular endothelial cells through PI3 kinase and MAP kinase signaling pathways.
Smiles
CC(O)=O.COc1ccc2c3c1oc(=O)c1c(CCN(C)C)cc(OC)c(oc2=O)c31
Molecular Formula
C22H23NO8
Molecular Weight
429.425
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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