PF-04628935

• Target:

  GHSR|||Others

• Related Pathways:

  GPCR/G Protein|||Others

• Bioactivity:

  PF-04628935 is a potent antagonist/inverse agonist of the ghrelin receptor, growth hormone secretagogue receptor 1a (GHS-R1a) with an IC50 of 4.6 nM. PF-04628935 is orally bioavailable and brain penetrant.

• Smiles:

  C(N1CC2(C1)CCN(C(CC3=CN4C(=N3)SC(C)=C4)=O)CC2)C5=C(Cl)C=C(C=C5)N6N=CC=N6

• Molecular Formula:

  C24H26ClN7OS

• Molecular Weight:

  496.03

• Shipping Conditions:

  Cool pack

• Storage Temperature:

  -20°C

• CAS Number:

  1383719-97-8