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MGS-0039

CAT: 0931-T28034-01Size: 25 mgDry Ice: NoHazardous: No
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CAT#:0931-T28034-01Size:25 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
569686-87-9
Target
GluR, Others
Related Pathways
Neuroscience, Others
Bioactivity
MGS-0039 is a group II metabotropic glutamate receptor (mgluR2/3) antagonist. Antidepressant-like action of group II mGlu receptor antagonists does not depend on serotonergic system activation. However, the AMPA receptor seems to play a key role in the antidepressant-like action of these compounds. Dopamine release in the NAc shell is regulated by mGlu 2/3 receptors.
Smiles
C(O)(=O)[C@]1(F)[C@@]2([C@]1(C[C@@H](OCC3=CC(Cl)=C(Cl)C=C3)[C@]2(C(O)=O)N)[H])[H]
Molecular Formula
C15H14Cl2FNO5
Molecular Weight
378.18
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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