DS-8587

• CAS Number :

  1356918-39-2

• Target :

  Others|||Antibacterial

• Related Pathways :

  Microbiology/Virology|||Others

• Bioactivity :

  DS-8587 is a DNA topoisomerase inhibitor. DS-8587 exhibits potent antibacterial activity against quinolone-resistant A. baumannii isolates that harbor mutations in quinolone resistance-determining regions. DS-8587 significantly reduces the number of viable bacteria in a murine model of F. necrophorum-induced liver abscess. In the presence of the efflux pump inhibitor 1- (1-napthylmethyl) -piperazine, no significant changes were observed in the MIC for DS-8587.

• Smiles :

  CC1=C2N([C@H]3[C@H](C3)F)C=C(C(C2=CC(F)=C1N4C[C@@]5([C@](C4)(CCC5)N)F)=O)C(O)=O.Cl.O.O

• Molecular Formula :

  C21H27ClF3N3O5

• Molecular Weight :

  493.9

• Shipping Conditions :

  Cool pack

• Storage Temperature :

  -20°C