DS-8587

CAT: 0931-T27211-01Size: 100 mgDry Ice: NoHazardous: No

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CAT#:0931-T27211-01Size:100 mg

Selected

24/48H Stock Items & 2 to 6 Weeks non Stock Items.

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CAS Number

1356918-39-2

Target

Others, Antibacterial

Related Pathways

Microbiology/Virology, Others

Bioactivity

DS-8587 is a DNA topoisomerase inhibitor. DS-8587 exhibits potent antibacterial activity against quinolone-resistant A. baumannii isolates that harbor mutations in quinolone resistance-determining regions. DS-8587 significantly reduces the number of viable bacteria in a murine model of F. necrophorum-induced liver abscess. In the presence of the efflux pump inhibitor 1- (1-napthylmethyl) -piperazine, no significant changes were observed in the MIC for DS-8587.

Smiles

CC1=C2N([C@H]3[C@H](C3)F)C=C(C(C2=CC(F)=C1N4C[C@@]5([C@](C4)(CCC5)N)F)=O)C(O)=O.Cl.O.O

Molecular Formula

C21H27ClF3N3O5

Molecular Weight

493.9

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

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