BMS 182874

CAT: 0931-T26841-01Size: 1 mgDry Ice: NoHazardous: No
CAT#:0931-T26841-01Size:1 mg
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CAS Number
153042-42-3
Target
Endothelin Receptor
Related Pathways
GPCR/G Protein
Purity
0.9973
Bioactivity
BMS 182874 is an orally effective and highly selective endothelin receptor ETA antagonist with an IC50 value of 0.150 ?M for ETA and a Ki value of 0.055 ?M for ETA.BMS 182874 is able to reduce arterial pressure in a rat hypertension model induced by Deoxycorticosterone acetate. BMS 182874 was able to reduce Deoxycorticosterone-induced arterial pressure in a rat model of hypertension and can be used to study cardiovascular disease.
Smiles
S(NC1=C(C)C(C)=NO1)(=O)(=O)C=2C3=C(C(N(C)C)=CC=C3)C=CC2
Molecular Formula
C17H19N3O3S
Molecular Weight
345.42
Shipping Conditions
Cool pack
Storage Temperature
-20°C

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Alternative Products

CatalogName
M34185-01BMS 182874
sc-361123ABMS 182874 hydrochloride
HY-118497RBMS 182874 (Standard)
HY-103458BMS 182874 (hydrochloride)

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