AG490

• Target:

  JAK|||STAT|||Autophagy|||EGFR

• Related Pathways:

  Tyrosine Kinase/Adaptors|||Autophagy|||Angiogenesis|||Stem Cells|||JAK/STAT signaling|||Chromatin/Epigenetic

• Purity:

  0.9985

• Bioactivity:

  AG490 (Tyrphostin B42) is an inhibitor of EGFR (IC50: 0.1 ?M) . It is 135-fold more selective for EGFR than ErbB2, also inhibits JAK2 with no effect to Lyn, Lck, Syk, Btk, and Src.

• Smiles:

  C(=C(/C(NCC1=CC=CC=C1)=O)\C#N)\C2=CC(O)=C(O)C=C2

• Molecular Formula:

  C17H14N2O3

• Molecular Weight:

  294.3

• Shipping Conditions:

  Cool pack

• Storage Temperature:

  -20°C

• CAS Number:

  133550-30-8