AG490

CAT: 0931-T2600-01Size: 10 mgDry Ice: NoHazardous: No
CAT#:0931-T2600-01Size:10 mg
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PRICE
AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
133550-30-8
Target
JAK|||STAT|||Autophagy|||EGFR
Related Pathways
Tyrosine Kinase/Adaptors|||Autophagy|||Angiogenesis|||Stem Cells|||JAK/STAT signaling|||Chromatin/Epigenetic
Purity
0.9985
Bioactivity
AG490 (Tyrphostin B42) is an inhibitor of EGFR (IC50: 0.1 ?M) . It is 135-fold more selective for EGFR than ErbB2, also inhibits JAK2 with no effect to Lyn, Lck, Syk, Btk, and Src.
Smiles
C(=C(/C(NCC1=CC=CC=C1)=O)\C#N)\C2=CC(O)=C(O)C=C2
Molecular Formula
C17H14N2O3
Molecular Weight
294.3
Shipping Conditions
Cool pack
Storage Temperature
-20°C

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