IMM-01

• Target:

  Apoptosis|||Ras|||GTPase

• Related Pathways:

  GPCR/G Protein|||Apoptosis|||MAPK

• Purity:

  0.9887

• Bioactivity:

  IMM-01 is a novel class of small-molecule agonists of the mammalian Diaphanous (mDia) -related formins, which act downstream of Rho GTPases to assemble actin filaments, and their organization with microfilaments to establish and maintain cell polarity during migration and asymmetric division. GTP-bound Rho activates mDia family members by disrupting the interaction between the DID and DAD autoregulatory domains, which releases the FH2 domain to modulate actin and microtubule dynamics[1].

• Smiles:

  CC(C)(C)NC(=S)N\N=C\C1=C(O)C=C(O)C=C1

• Molecular Formula:

  C12H17N3O2S

• Molecular Weight:

  267.35

• Shipping Conditions:

  Cool pack

• Storage Temperature:

  -20°C

• CAS Number:

  218795-74-5