Dolutegravir sodium

• Target:

  HIV Protease

• Related Pathways:

  Proteases/Proteasome|||Microbiology/Virology

• Purity:

  0.9974

• Bioactivity:

  Dolutegravir sodium (GSK-1349572A) salt (DTG; GSK1349572) is an HIV integrase inhibitor (IC50: 2.7 nM), modest activity against raltegravir-resistant signature mutants Y143R, Q148K, N155H, and G140S/Q148H.

• Smiles:

  [Na+].C[C@@H]1CCO[C@H]2Cn3cc(C(=O)NCc4ccc(F)cc4F)c(=O)c([O-])c3C(=O)N12

• Molecular Formula:

  C20H18F2N3NaO5

• Molecular Weight:

  441.36

• Shipping Conditions:

  Cool pack

• Storage Temperature:

  -20°C

• CAS Number:

  1051375-19-9