Dolutegravir

• Target:

  HIV Protease

• Related Pathways:

  Proteases/Proteasome|||Microbiology/Virology

• Purity:

  0.9975

• Bioactivity:

  Dolutegravir (GSK1349572) (IC50=2.7 nM), a two-metal-binding HIV integrase inhibitor, exhibits medium activity against raltegravir-resistant signature mutants Y143R, Q148K, N155H, and G140S/Q148H.

• Smiles:

  C[C@@H]1CCO[C@H]2Cn3cc(C(=O)NCc4ccc(F)cc4F)c(=O)c(O)c3C(=O)N12

• Molecular Formula:

  C20H19F2N3O5

• Molecular Weight:

  419.38

• Shipping Conditions:

  Cool pack

• Storage Temperature:

  -20°C

• CAS Number:

  1051375-16-6