Dolutegravir O-β-D-Glucuronide

CAT: 0931-T36794Size: 2500 μgDry Ice: NoHazardous: No

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CAT#:0931-T36794Size:2500 μg

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24/48H Stock Items & 2 to 6 Weeks non Stock Items.

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CAS Number

1485692-21-4

Target

Others

Related Pathways

Others

Bioactivity

Dolutegravir O-β-D-glucuronide is a metabolite of the HIV integrase inhibitor dolutegravir .1It is formed from dolutegravir primarily by the UDP-glucuronosyltransferase (UGT) isoform UGT1A1in vivobut is also metabolized by UGT1A9 in human liver and kidney microsomes and UGT1A3 in human intestinal microsomes.2,1

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[H][C@]12Cn3cc(C(=O)NCc4ccc(F)cc4F)c(=O)c(O[C@@H]4O[C@@H]([C@@H](O)[C@H](O)[C@H]4O)C(O)=O)c3C(=O)N1[C@H](C)CCO2

Molecular Formula

C26H27F2N3O11

Molecular Weight

595.509

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

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Dolutegravir O-β-D-Glucuronide

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