Motesanib

• Target :

  VEGFR|||c-Kit

• Related Pathways :

  Angiogenesis|||Tyrosine Kinase/Adaptors

• Purity :

  0.9909

• Bioactivity :

  Motesanib (AMG 706) is an orally bioavailable receptor tyrosine kinase inhibitor with potential antineoplastic activity. AMG 706 selectively targets and inhibits vascular endothelial growth factor (VEGFR), platelet-derived growth factor (PDGFR), Kit, and Ret receptors, thereby inhibiting angiogenesis and cellular proliferation.

• Smiles :

  CC1(C)CNc2cc(NC(=O)c3cccnc3NCc3ccncc3)ccc12

• Molecular Formula :

  C22H23N5O

• Molecular Weight :

  373.45

• Shipping Conditions :

  Cool pack

• Storage Temperature :

  -20°C

• CAS Number :

  453562-69-1