Motesanib

• Target:

  VEGFR|||c-Kit

• Related Pathways:

  Angiogenesis|||Tyrosine Kinase/Adaptors

• Purity:

  0.9909

• Bioactivity:

  Motesanib (AMG 706) is an orally bioavailable receptor tyrosine kinase inhibitor with potential antineoplastic activity. AMG 706 selectively targets and inhibits vascular endothelial growth factor (VEGFR), platelet-derived growth factor (PDGFR), Kit, and Ret receptors, thereby inhibiting angiogenesis and cellular proliferation.

• Smiles:

  CC1(C)CNc2cc(NC(=O)c3cccnc3NCc3ccncc3)ccc12

• Molecular Formula:

  C22H23N5O

• Molecular Weight:

  373.45

• Shipping Conditions:

  Cool pack

• Storage Temperature:

  -20°C

• CAS Number:

  453562-69-1