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Proguanil

CAT: 0931-T22409-01Size: 10 mgDry Ice: NoHazardous: No
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CAT#:0931-T22409-01Size:10 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
500-92-5
Target
Parasite, DNA/RNA Synthesis, Antifolate
Related Pathways
DNA Damage/DNA Repair, Cell Cycle/Checkpoint, Microbiology/Virology
Purity
0.996
Bioactivity
Proguanil (Chloroguanide) is a prophylactic antimalarial drug that acts primarily through its active metabolite, Cycloguanil, which inhibits the dihydrofolate reductase (DHFR) enzyme of Plasmodium falciparum, preventing the synthesis of purines and pyrimidines and inhibiting the growth and reproduction of the parasite.
Smiles
ClC1=CC=C(C=C1)NC(=N)NC(=N)NC(C)C
Molecular Formula
C11H16ClN5
Molecular Weight
253.73
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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