Dactolisib

• Target :

  Autophagy|||mTOR|||ATM/ATR|||PI3K

• Related Pathways :

  Autophagy|||DNA Damage/DNA Repair|||PI3K/Akt/mTOR signaling

• Purity :

  0.9985

• Bioactivity :

  Dactolisib (BEZ235) is an orally bioavailable inhibitor of PI3K and mTOR, with IC50 values of 4 nM for p110?, 5 nM for p110?, 7 nM for p110?, 75 nM for p110?, and 20.7 nM for mTOR.

• Smiles :

  O=C1N(C=2C=3C(N=CC2N1C)=CC=C(C3)C4=CC5=C(N=C4)C=CC=C5)C6=CC=C(C(C#N)(C)C)C=C6

• Molecular Formula :

  C30H23N5O

• Molecular Weight :

  469.54

• Shipping Conditions :

  Cool pack

• Storage Temperature :

  -20°C

• CAS Number :

  915019-65-7