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CPI-455 HCl

CAT: 0931-T22299-01Size: 25 mgDry Ice: NoHazardous: No
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CAT#:0931-T22299-01Size:25 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
2095432-28-1
Target
Histone Demethylase
Related Pathways
Chromatin/Epigenetic
Bioactivity
CPI-455 is a specific KDM5 inhibitor with IC50 value of 10 ± 1 nM for full-length KDM5A in enzymatic assays, elevating global levels of H3K4 trimethylation (H3K4me3) and decreased the number of DTPs in multiple cancer cell line models treated with targeted agents or standard chemotherapy.
Smiles
Cl.CC(C)c1c([nH]c2c(cnn2c1=O)C#N)-c1ccccc1
Molecular Formula
C16H15ClN4O
Molecular Weight
314.77
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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