UMB-32

• Target :

  Epigenetic Reader Domain|||Others

• Related Pathways :

  Chromatin/Epigenetic|||Others

• Bioactivity :

  UMB-32 is a potent and selective BRD4 inhibitor, demonstrating an affinity for BRD4 with a dissociation constant (K d) of 550 nM and an inhibitory concentration 50 (IC 50) of 637 nM. Moreover, UMB-32 exhibits effectiveness against TAF1, a bromodomain-containing transcription factor [1].

• Smiles :

  N(C(C)(C)C)C1=C(N=C2N1C=CN=C2)C3=CC=C(C=C3)C=4C(C)=NOC4C

• Molecular Formula :

  C21H23N5O

• Molecular Weight :

  361.44

• Shipping Conditions :

  Cool pack

• Storage Temperature :

  -20°C

• CAS Number :

  1635437-39-6