ZJ 43

• Target :

  GluR|||Aminopeptidase

• Related Pathways :

  Neuroscience|||Metabolism

• Bioactivity :

  ZJ43 is a potent inhibitor of glutamate carboxypeptidase II (K (i) = 0.8 nM) and III (K (i) = 23 nM) that inhibits the hydrolysis of NAAG (IC50 = 2.4 nM) . ZJ43 sufficiently activates group II mGluR and reduces some of the behavioral effects of PCP. ZJ43 shows an analgesic effect in neuropathic and inflammatory and pain models [1].

• Smiles :

  CC(C)C[C@H](NC(N[C@@H](CCC(O)=O)C(O)=O)=[O]CC(C)C[C@H](NC(=O)N[C@@H](CCC(O)=O)C(O)=O)C(O)=O)C(O)=O

• Molecular Formula :

  C24H39N4O14

• Molecular Weight :

  607.59

• Shipping Conditions :

  Cool pack

• Storage Temperature :

  -20°C

• CAS Number :

  723331-20-2