ZJ 43

CAT: 0931-T21837-01Size: 5 mgDry Ice: NoHazardous: No
CAT#:0931-T21837-01Size:5 mg
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AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
723331-20-2
Target
GluR|||Aminopeptidase
Related Pathways
Neuroscience|||Metabolism
Bioactivity
ZJ43 is a potent inhibitor of glutamate carboxypeptidase II (K (i) = 0.8 nM) and III (K (i) = 23 nM) that inhibits the hydrolysis of NAAG (IC50 = 2.4 nM) . ZJ43 sufficiently activates group II mGluR and reduces some of the behavioral effects of PCP. ZJ43 shows an analgesic effect in neuropathic and inflammatory and pain models [1].
Smiles
CC(C)C[C@H](NC(N[C@@H](CCC(O)=O)C(O)=O)=[O]CC(C)C[C@H](NC(=O)N[C@@H](CCC(O)=O)C(O)=O)C(O)=O)C(O)=O
Molecular Formula
C24H39N4O14
Molecular Weight
607.59
Shipping Conditions
Cool pack
Storage Temperature
-20°C

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