JNJ-28312141

• Target :

  Others|||c-Fms

• Related Pathways :

  Tyrosine Kinase/Adaptors|||Others

• Bioactivity :

  JNJ-28312141 is an orally active CSF1R inhibitor and a FLT3 inhibitor. JNJ-28312141 is a new agent with potential therapeutic activity in acute myeloid leukemia and in settings where CSF-1-dependent macrophages and osteoclasts contribute to tumor growth and skeletal events.

• Smiles :

  N(C(=O)C=1NC(C#N)=CN1)C2=C(C=C(C=C2)C3CCN(C(CN(C)C)=O)CC3)C=4CCCCC4

• Molecular Formula :

  C26H32N6O2

• Molecular Weight :

  460.57

• Shipping Conditions :

  Cool pack

• Storage Temperature :

  -20°C

• CAS Number :

  885692-52-4