JNJ-54175446

• Target :

  P2X Receptor

• Related Pathways :

  Neuroscience|||Membrane transporter/Ion channel

• Purity :

  >99.99%

• Bioactivity :

  JNJ-54175446 (JNJ-5446) is a CNS-permeable and selective P2X7 receptor antagonist that attenuates the release of IL-1?/IL-18 from microglia, and may be used in the study of depression.

• Smiles :

  C[C@H]1N(CCc2c1nnn2-c1ncc(F)cn1)C(=O)c1cccc(c1Cl)C(F)(F)F

• Molecular Formula :

  C18H13ClF4N6O

• Molecular Weight :

  440.78

• Shipping Conditions :

  Cool pack

• Storage Temperature :

  -20°C

• CAS Number :

  1627902-21-9