JNJ-46356479

• Target :

  Others|||GluR

• Related Pathways :

  Neuroscience|||Others

• Bioactivity :

  JNJ-46356479 is a Selective and Orally Bioavailable mGlu2 receptor Positive Allosteric Modulator (PAM) . JNJ-46356479 showed mGlu2 PAM EC50=78 nM; mGlu2 PAM Emax (%) = 256.

• Smiles :

  C(F)(F)(F)C=1C=2N(C(CC3CC3)=NN2)C=CC1CN4CCN(CC4)C5=C(F)C=C(F)C=C5

• Molecular Formula :

  C22H22F5N5

• Molecular Weight :

  451.44

• Shipping Conditions :

  Cool pack

• Storage Temperature :

  -20°C

• CAS Number :

  1254979-66-2