TAK-441

• Target :

  Hedgehog/Smoothened

• Related Pathways :

  Stem Cells|||GPCR/G Protein

• Purity :

  0.9982

• Bioactivity :

  TAK-441 is an orally active inhibitor of Hedgehog signaling (IC50 = 4.4 nM) with potent antitumor activity. TAK-441 suppresses transcription factor Gli1 mRNA expression and tumor growth.

• Smiles :

  O(CC(F)(F)F)C=1C2=C(N(C)C1C(NC3CCN(C(CO)=O)CC3)=O)C=C(CC)N(CC(=O)C4=CC=CC=C4)C2=O

• Molecular Formula :

  C28H31F3N4O6

• Molecular Weight :

  576.56

• Shipping Conditions :

  Cool pack

• Storage Temperature :

  -20°C

• CAS Number :

  1186231-83-3