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CX-5461

CAT: 0931-T2100-01Size: 2 mgDry Ice: NoHazardous: No
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CAT#:0931-T2100-01Size:2 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
1138549-36-6
Target
DNA/RNA Synthesis
Related Pathways
DNA Damage/DNA Repair, Cell Cycle/Checkpoint
Purity
0.994
Bioactivity
CX5461 is an rRNA synthesis inhibitor with oral activity that inhibits Pol I-driven rRNA transcription. CX5461 activates the DNA damage response and has antitumor activity in tumors such as ovarian cancer.
Smiles
CN1CCCN(CC1)c1ccc2c(n1)n1c3ccccc3sc1c(C(=O)NCc1cnc(C)cn1)c2=O
Molecular Formula
C27H27N7O2S
Molecular Weight
513.61
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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