SB 224289

• Target :

  Others|||5-HT Receptor

• Related Pathways :

  GPCR/G Protein|||Neuroscience|||Others

• Bioactivity :

  SB 224289 is a selective antagonist of 5-HT1B receptor with pKi of 8.2. It is a centrally active following oral administration in vivo. SB 224289 displays 60-fold selectivity over 5-HT1D, 5-HT1A, 5-HT1E, 5-HT1F, 5-HT2A and 5-HT2C receptors in radioligand binding and functional assays.

• Smiles :

  C(=O)(N1C=2C=C3C4(COC3=CC2CC1)CCN(C)CC4)C5=CC=C(C=C5)C6=C(C)C=C(C=C6)C=7N=C(C)ON7

• Molecular Formula :

  C32H32N4O3

• Molecular Weight :

  520.62

• Shipping Conditions :

  Cool pack

• Storage Temperature :

  -20°C

• CAS Number :

  180083-23-2