PR-619

• Target :

  Autophagy|||Apoptosis|||DUB

• Related Pathways :

  Cell Cycle/Checkpoint|||Ubiquitination|||Apoptosis|||DNA Damage/DNA Repair|||Autophagy

• Purity :

  >99.99%

• Bioactivity :

  PR-619 (2,6-Diamino-3,5-dithiocyanopyridine) is a DUB inhibitor that inhibits USP2/4/5/7/8 (EC50=7.2/3.93/8.61/6.86/4.9 ?M) . PR-619 induces endoplasmic reticulum stress and activates autophagy.

• Smiles :

  Nc1nc(N)c(SC#N)cc1SC#N

• Molecular Formula :

  C7H5N5S2

• Molecular Weight :

  223.28

• Shipping Conditions :

  Cool pack

• Storage Temperature :

  -20°C

• CAS Number :

  2645-32-1