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Ipatasertib-NH2

CAT: 0931-T18053-01Size: 100 mgDry Ice: NoHazardous: No
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CAT#:0931-T18053-01Size:100 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
1001382-14-4
Target
Ligands for Target Protein for PROTAC, Others
Related Pathways
PROTAC, Others
Bioactivity
Ipatasertib-NH2 (GDC-0068-NH2; RG7440-NH2) is a ligand for the target protein AKT used in PROTAC, binding to lenalidomide, a ligand of ubiquitin E3 ligase cereblon (CRBN), via a ten-hydrocarbon linker to form INY-03-041 for AKT degradation[1].
Smiles
C[C@H]1C2=C(N=CN=C2[C@H](O)C1)N3CCN(C([C@H](CN)C4=CC=C(Cl)C=C4)=O)CC3
Molecular Formula
C21H26ClN5O2
Molecular Weight
415.92
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

1001382-14-4

PubChem
cas1001382-14-4
PubChem LinkClick here

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