DM4-SMCC

CAT: 0931-T17833-01Size: 100 mgDry Ice: NoHazardous: No
CAT#:0931-T17833-01Size:100 mg
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CAS Number
1228105-52-9
Target
Drug-Linker Conjugates for ADC
Related Pathways
Antibody-drug Conjugate/ADC Related
Bioactivity
DM4-SMCC, a non-cleavable drug-linker conjugate for antibody-drug conjugates (ADC), leverages the antitumor efficacy of DM4 (an antitubulin agent) through attachment with the SMCC linker, exhibiting antitumor activity[1].
Smiles
C[C@]12[C@@](O1)([C@H](C)[C@@]3(C[C@](O)([C@H](OC)/C=C/C=C(\C)/CC4=CC(N(C)C(=O)C[C@@H]2OC([C@@H](N(C(CCC(SC5C(=O)N(CC6CCC(C(ON7C(=O)CCC7=O)=O)CC6)C(=O)C5)(C)C)=O)C)C)=O)=C(Cl)C(OC)=C4)NC(=O)O3)[H])[H]
Molecular Formula
C54H72ClN5O16S
Molecular Weight
1114.69
Shipping Conditions
Cool pack
Storage Temperature
-20°C

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