DM4-SMCC

• Target:

  Drug-Linker Conjugates for ADC

• Related Pathways:

  Antibody-drug Conjugate/ADC Related

• Bioactivity:

  DM4-SMCC, a non-cleavable drug-linker conjugate for antibody-drug conjugates (ADC), leverages the antitumor efficacy of DM4 (an antitubulin agent) through attachment with the SMCC linker, exhibiting antitumor activity[1].

• Smiles:

  C[C@]12[C@@] (O1) ([C@H] (C) [C@@]3 (C[C@] (O) ([C@H] (OC) /C=C/C=C (\C) /CC4=CC (N (C) C (=O) C[C@@H]2OC ([C@@H] (N (C (CCC (SC5C (=O) N (CC6CCC (C (ON7C (=O) CCC7=O) =O) CC6) C (=O) C5) (C) C) =O) C) C) =O) =C (Cl) C (OC) =C4) NC (=O) O3) [H]) [H]

• Molecular Formula:

  C54H72ClN5O16S

• Molecular Weight:

  1114.69

• Shipping Conditions:

  Cool pack

• Storage Temperature:

  -20°C

• CAS Number:

  1228105-52-9