DM4-SMCC

• Target :

  Drug-Linker Conjugates for ADC

• Related Pathways :

  Antibody-drug Conjugate/ADC Related

• Bioactivity :

  DM4-SMCC, a non-cleavable drug-linker conjugate for antibody-drug conjugates (ADC), leverages the antitumor efficacy of DM4 (an antitubulin agent) through attachment with the SMCC linker, exhibiting antitumor activity[1].

• Smiles :

  C[C@]12[C@@](O1)([C@H](C)[C@@]3(C[C@](O)([C@H](OC)/C=C/C=C(\C)/CC4=CC(N(C)C(=O)C[C@@H]2OC([C@@H](N(C(CCC(SC5C(=O)N(CC6CCC(C(ON7C(=O)CCC7=O)=O)CC6)C(=O)C5)(C)C)=O)C)C)=O)=C(Cl)C(OC)=C4)NC(=O)O3)[H])[H]

• Molecular Formula :

  C54H72ClN5O16S

• Molecular Weight :

  1114.69

• Shipping Conditions :

  Cool pack

• Storage Temperature :

  -20°C

• CAS Number :

  1228105-52-9