Products for Research Use Only

ZK 216348

CAT: 0931-T17291-01Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0931-T17291-01Size:5 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
669073-68-1
Target
Glucocorticoid Receptor, Progesterone Receptor
Related Pathways
Others, Endocrinology/Hormones
Bioactivity
ZK 216348 is a non-steroidal selective glucocorticoid receptor agonist with an IC50 of 20.3 nM. ZK 216348 also binds to progesterone receptors and mineralocorticoid receptors with IC50 values of 20.4 nM and 79.9 nM, respectively, and may be useful for studying inflammatory bowel disease (IBD) .
Smiles
C(CC(C(NC=1C=C2C(=CC1)C(=O)ON=C2C)=O)(C(F)(F)F)O)(C)(C)C3=C4C(CCO4)=CC=C3
Molecular Formula
C24H23F3N2O5
Molecular Weight
476.45
Shipping Conditions
Ice Packs
Storage Temperature
-20°C