Products for Research Use Only

ZK 756326

CAT: 0931-T3360-01Size: 2 mgDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0931-T3360-01Size:2 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
CAS Number
874911-96-3
Target
CCR
Related Pathways
GPCR/G Protein, Immunology/Inflammation, Microbiology/Virology
Purity
0.9943
Bioactivity
ZK 756326 is a selective, non-peptide CCR8 chemokine receptor agonist (IC50: 1.8 μM, in human; 2.6 μM, in mouse) . Displays no activity at CCR4/5 and CXCR3/4 and shows higher 28-fold selectivity over 26 other GPCRs (less selective at α2A and 5-HT receptors) . Induces chemotaxis and inhibits Env-mediated (HIV) cell-cell fusion.
Smiles
Cl.Cl.OCCOCCN1CCN(Cc2cccc(Oc3ccccc3)c2)CC1
Molecular Formula
C21H28N2O3
Molecular Weight
356.46
Shipping Conditions
Ice Packs
Storage Temperature
-20°C