Tauroursodeoxycholate dihydrate

• Target:

  IRE1|||ERK|||JNK|||Apoptosis|||NF-?B|||Caspase|||Akt|||ROS|||Endogenous Metabolite

• Related Pathways:

  Cell Cycle/Checkpoint|||PI3K/Akt/mTOR signaling|||Apoptosis|||Proteases/Proteasome|||Immunology/Inflammation|||NF-?B|||MAPK|||Cytoskeletal Signaling|||Metabolism

• Purity:

  0.9982

• Bioactivity:

  Tauroursodeoxycholate (TUDCA , Taurolite) dihydrate is a water-soluble bile acid with endoplasmic reticulum stress inhibitory, mitochondrial stabilizing, and anti-apoptotic effects, which significantly reduces the expression of apoptotic molecules, such as Caspase-3 and Caspase-12, and inhibits ERK, reducing endoplasmic reticulum stress mediated cell death.

• Smiles:

  C[C@@]12[C@](CC[C@]2([H])[C@H](C)CCC(NCCS(=O)(O)=O)=O)([H])[C@@]3([H])[C@@](CC1)([H])[C@@]4([C@](C[C@@H](CC4)O)([H])C[C@@H]3O)C.O.O

• Molecular Formula:

  C26H49NO8S

• Molecular Weight:

  535.73

• Shipping Conditions:

  Cool pack

• Storage Temperature:

  -20°C

• CAS Number:

  117609-50-4