Tauroursodeoxycholate dihydrate

CAT: 0931-T16998-01Size: 25 mgDry Ice: NoHazardous: No
CAT#:0931-T16998-01Size:25 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
117609-50-4
Target
IRE1|||ERK|||JNK|||Apoptosis|||NF-?B|||Caspase|||Akt|||ROS|||Endogenous Metabolite
Related Pathways
Cell Cycle/Checkpoint|||PI3K/Akt/mTOR signaling|||Apoptosis|||Proteases/Proteasome|||Immunology/Inflammation|||NF-?B|||MAPK|||Cytoskeletal Signaling|||Metabolism
Purity
0.9982
Bioactivity
Tauroursodeoxycholate (TUDCA , Taurolite) dihydrate is a water-soluble bile acid with endoplasmic reticulum stress inhibitory, mitochondrial stabilizing, and anti-apoptotic effects, which significantly reduces the expression of apoptotic molecules, such as Caspase-3 and Caspase-12, and inhibits ERK, reducing endoplasmic reticulum stress mediated cell death.
Smiles
C[C@@]12[C@](CC[C@]2([H])[C@H](C)CCC(NCCS(=O)(O)=O)=O)([H])[C@@]3([H])[C@@](CC1)([H])[C@@]4([C@](C[C@@H](CC4)O)([H])C[C@@H]3O)C.O.O
Molecular Formula
C26H49NO8S
Molecular Weight
535.73
Shipping Conditions
Cool pack
Storage Temperature
-20°C

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