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TAS05567

CAT: 0931-T16995-01Size: 25 mgDry Ice: NoHazardous: No
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CAT#:0931-T16995-01Size:25 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
1429038-15-2
Target
JAK, c-RET, FLT, Syk
Related Pathways
Chromatin/Epigenetic, Tyrosine Kinase/Adaptors, Angiogenesis, Apoptosis, Stem Cells, JAK/STAT signaling
Bioactivity
TAS05567 is a potent, highly selective, and ATP-competitive Syk inhibitor (IC50: 0.37 nM), showing >70% inhibition of Syk and four other kinases [FLT3 (IC50: 10 nM), JAK2 (IC50: 4.8 nM), KDR (IC50: 600 nM), RET (IC50: 29 nM) ] in a panel of 192 kinases.
Smiles
CC=1C=2C(=CN(C(C)(C)C)N2)C=C(NC=3C(C(N)=O)=NN=C(N[C@H]4[C@@H](N)COCC4)N3)C1
Molecular Formula
C21H29N9O2
Molecular Weight
439.51
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

Alternative Products

CatalogName
GTR19203037-01TAS05567

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