TAK-220

• Target :

  CCR|||HIV Protease

• Related Pathways :

  Immunology/Inflammation|||Proteases/Proteasome|||Microbiology/Virology|||GPCR/G Protein

• Bioactivity :

  TAK-220 is a selective and orally bioavailable CCR5 antagonist with IC50 values of 3.5 nM for RANTES binding inhibition and 1.4 nM for MIP-1? binding inhibition to CCR5.

• Smiles :

  CC(=O)N1CCC(CC1)C(=O)N(CCCN1CCC(Cc2ccc(cc2)C(N)=O)CC1)c1ccc(C)c(Cl)c1

• Molecular Formula :

  C31H41ClN4O3

• Molecular Weight :

  553.14

• Shipping Conditions :

  Cool pack

• Storage Temperature :

  -20°C

• CAS Number :

  333994-00-6