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SB-218078

CAT: 0931-T16848Size: 1 mgDry Ice: NoHazardous: No
CAT#:0931-T16848Size:1 mg
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PRICE
AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
135897-06-2
Target
PKC|||Apoptosis|||Chk|||CDK
Related Pathways
Chromatin/Epigenetic|||Apoptosis|||Cell Cycle/Checkpoint|||Cytoskeletal Signaling
Bioactivity
SB-218078 is less potently inhibits Cdc2 (IC50: 250 nM) and PKC (IC50: 1000 nM) . SB-218078 is a potent, ATP-competitive, and cell-permeable checkpoint kinase 1 inhibitor that inhibits Chk1 phosphorylation of cdc25C (IC50: 15 nM) .
Smiles
O=C1NC(=O)c2c1c1c3ccccc3n3C4CCC(O4)n4c5ccccc5c2c4c13
Molecular Formula
C24H15N3O3
Molecular Weight
393.39
Shipping Conditions
Cool pack
Storage Temperature
-20°C

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