RET V804M-IN-1

CAT: 0931-T8467-01Size: 1 mgDry Ice: NoHazardous: No

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CAT#:0931-T8467-01Size:1 mg

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24/48H Stock Items & 2 to 6 Weeks non Stock Items.

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CAS Number

2414909-94-5

Target

C-RET

Related Pathways

Apoptosis, Tyrosine Kinase/Adaptors

Purity

0.9962

Bioactivity

RET V804M-IN-1 (RETV804M kinase inhibitor) is a wt-RET -selective RETV804M kinase inhibitors (IC50 = 20 nM) .

Smiles

NC(=O)c1ccc(cc1)-c1cnn2ccc(NCc3cccnc3)nc12

Molecular Formula

C19H16N6O

Molecular Weight

344.37

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Chemical Information

4-(5-((Pyridin-3-ylmethyl)amino)pyrazolo[1,5-a]pyrimidin-3-yl)benzamide

CAS Number	2414909-94-5
PubChem CID	145994823
IUPAC Name	4-[5-(pyridin-3-ylmethylamino)pyrazolo[1,5-a]pyrimidin-3-yl]benzamide
Molecular Formula	C19H16N6O
Molecular Weight	344.4
XLogP	1.6
Topological Polar Surface Area	98.2
Hydrogen Bond Donor Count	2
Hydrogen Bond Acceptor Count	5
Rotatable Bond Count	5
Heavy Atom Count	26
Formal Charge	0
Complexity	481

SMILES

C1=CC(=CN=C1)CNC2=NC3=C(C=NN3C=C2)C4=CC=C(C=C4)C(=O)N

InChI

InChI=1S/C19H16N6O/c20-18(26)15-5-3-14(4-6-15)16-12-23-25-9-7-17(24-19(16)25)22-11-13-2-1-8-21-10-13/h1-10,12H,11H2,(H2,20,26)(H,22,24)

InChIKey

LMGXQBQAUALFTB-UHFFFAOYSA-N

Chemical Structure

2D Structure

CAS: 2414909-94-5

CID: 145994823

Formula: C19H16N6O

MW: 344.4

Interactive 3D Structure

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View on PubChem Raw 3D data

Computed Properties

Property	Value
Molecular Weight	344.4
XLogP3	1.6
Hydrogen Bond Donor Count	2
Hydrogen Bond Acceptor Count	5
Rotatable Bond Count	5
Exact Mass	344.13855916
Monoisotopic Mass	344.13855916
Topological Polar Surface Area	98.2 Å²
Heavy Atom Count	26
Formal Charge	0
Complexity	481
Isotope Atom Count	0
Defined Atom Stereocenter Count	0
Undefined Atom Stereocenter Count	0
Defined Bond Stereocenter Count	0
Undefined Bond Stereocenter Count	0
Covalently-Bonded Unit Count	1
Compound Is Canonicalized	Yes

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T203439-01	RET-IN-28
T201034-01	RET-IN-27
T9673-01	RET-IN-3
T63772-01	RET-IN-5
T81296-01	RET-IN-26
T79099-01	RET-IN-23

Alternative Products

Catalog	Name
EP176311-01	RET V804M-IN-1
MBS517505-01	RET (V804M), Active
MBS517519-01	KIF5B-RET (V804M), Active
ABC-X0360F	CCDC6-RET (V804M) BaF3 Cell Line
ABC-X0354F	KIF5B-RET (V804M-G810S) BaF3 Cell Line
HY-E70779	RET V804M Recombinant Human Active Protein Kinase
MBS518016-01	Recombinant Human RET Protein (V804M, G810S, GST Tag), Active
CSC-RO0398	Human KIF5B-RET-V804M Stable Cell Line - BaF3
OF59775-01	1,1,1,1,1-Kestoheptaose
N2864-5.1	1,1,1,1-Kestohexaose

RET V804M-IN-1

Chemical Information

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