Products for Research Use Only
RegisterLogin

Phenoxodiol

CAT: 0931-T16522-05Size: 25 mgDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0931-T16522-05Size:25 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
CAS Number
81267-65-4
Target
Apoptosis, Caspase, p53, Topoisomerase, IAP
Related Pathways
Proteases/Proteasome, Apoptosis, DNA Damage/DNA Repair
Purity
0.9918
Bioactivity
Phenoxodiol (Idronoxil) activates the mitochondrial caspase system, inhibits X-linked inhibitor of apoptosis (XIAP), disrupts FLICE inhibitory protein (FLIP) expression, and sensitizes the cancer cells to Fas-mediated apoptosis. Phenoxodiol induces cell cycle arrest in the G1/S phase of the cell cycle and upregulates p21WAF1 via a p53 independent manner. Phenoxodiol also inhibits DNA topoisomerase II.
Smiles
Oc1ccc(cc1)C1=Cc2ccc(O)cc2OC1
Molecular Formula
C15H12O3
Molecular Weight
240.25
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

Chemical Information

Phenoxodiol

Idronoxil is a substance that is being studied in the treatment of cancer. It belongs to the family of drugs called signal transduction inhibitors.

CAS Number81267-65-4
PubChem CID219100
IUPAC Name3-(4-hydroxyphenyl)-2H-chromen-7-ol
Molecular FormulaC15H12O3
Molecular Weight240.25
XLogP2.7
Topological Polar Surface Area49.7
Hydrogen Bond Donor Count2
Hydrogen Bond Acceptor Count3
Rotatable Bond Count1
Heavy Atom Count18
Formal Charge0
Complexity318
SMILES
C1C(=CC2=C(O1)C=C(C=C2)O)C3=CC=C(C=C3)O
InChI
InChI=1S/C15H12O3/c16-13-4-1-10(2-5-13)12-7-11-3-6-14(17)8-15(11)18-9-12/h1-8,16-17H,9H2
InChIKey
ZZUBHVMHNVYXRR-UHFFFAOYSA-N
Chemical Structure
2D Structure
2D structure of Phenoxodiol
CAS: 81267-65-4
CID: 219100
Formula: C15H12O3
MW: 240.25
Interactive 3D Structure
Loading 3D structure...
View on PubChemRaw 3D data
Computed Properties
PropertyValue
Molecular Weight240.25
XLogP32.7
Hydrogen Bond Donor Count2
Hydrogen Bond Acceptor Count3
Rotatable Bond Count1
Exact Mass240.078644241
Monoisotopic Mass240.078644241
Topological Polar Surface Area49.7 Ų
Heavy Atom Count18
Formal Charge0
Complexity318
Isotope Atom Count0
Defined Atom Stereocenter Count0
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently-Bonded Unit Count1
Compound Is CanonicalizedYes

Alternative Products

CatalogName
BA2912-25Phenoxodiol
A21147-2Phenoxodiol 2mg
A21147-25Phenoxodiol 25mg
A21147-1Phenoxodiol 1mg
A21147-10Phenoxodiol 10mg
A21147-5Phenoxodiol 5mg
HY-13721R-01Phenoxodiol (Standard)
A21147-100Phenoxodiol 100mg
A21147-50Phenoxodiol 50mg
C14377-5mgPhenoxodiol (Haginin E)

Popular Products