PF-4191834

• Target :

  Lipoxygenase

• Related Pathways :

  Metabolism

• Purity :

  >99.99%

• Bioactivity :

  PF-4191834 is a noniron chelating and non-redox inhibitor of the 5-Lipoxygenase (5-LOX) with an IC50 of 229 nM. PF-4191834 shows ~300-fold selectivity for 5-LOX over 12-LOX and 15-LOX and displays no activity toward the cyclooxygenase enzymes. PF-4191834

• Smiles :

  Cn1nccc1-c1ccc(Sc2cccc(c2)C2(CCOCC2)C(N)=O)cc1

• Molecular Formula :

  C22H23N3O2S

• Molecular Weight :

  393.5

• Shipping Conditions :

  Cool pack

• Storage Temperature :

  -20°C

• CAS Number :

  1029317-21-2