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Nimbolide

CAT: 0931-T16324-01Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0931-T16324-01Size:1 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
25990-37-8
Target
CDK, Wnt/beta-catenin, Apoptosis, NF-κB
Related Pathways
NF-κB, Cell Cycle/Checkpoint, Cytoskeletal Signaling, Stem Cells, Apoptosis
Purity
0.994
Bioactivity
Nimbolide suppresses CDK4/CDK6 kinase activity. Nimbolide inhibits the NF-κB, Wnt, PI3K-Akt, MAPK, and JAK-STAT signaling pathways. Nimbolide causes apoptosis through the inactivation of NF-κB. Nimbolide is a triterpene derived from the leaves and flowers of neem (Azadirachta indica L) .
Smiles
C[C@]12[C@]3([C@]([C@@]4([C@](C)([C@@H]1CC(OC)=O)C=5[C@](O4)(C[C@H](C5C)C=6C=COC6)[H])[H])(OC(=O)[C@]3(C)C=CC2=O)[H])[H]
Molecular Formula
C27H30O7
Molecular Weight
466.52
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

Alternative Products

CatalogName
1891-25Nimbolide
A13976-10Nimbolide 10mg
HY-116035RNimbolide (Standard)
A13976-100Nimbolide 100mg

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