Products for Research Use Only

Nimbolide

CAT: 0026-1891-25Size: 25 mgDry Ice: NoHazardous: No
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CAT#:0026-1891-25Size:25 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
A terpenoid lactone derived from Azadirachta indica (Neem tree) that displays a variety of biological activities including anti-malarial and anticancer activity. Recently it has also been shown that nimbolide sensitizes colon cancer cells to TRAIL-induced apoptosis through three distinct mechanisms: reactive oxygen species and ERK-mediated up-regulation of DR5 and DR4, downregulation of cell survival proteins, and up-regulation of pro-apoptotic proteins p53 and Bax.
Shipping Conditions
gel pack
Storage Conditions
-20°C
Shelf Life
36 months