NI-42

• Target :

  Epigenetic Reader Domain

• Related Pathways :

  Chromatin/Epigenetic

• Purity :

  0.9918

• Bioactivity :

  NI-42 is a structurally orthogonal chemical probe for the BRPFs and is biased. It effective inhibitor of the BRD of the BRPFs (IC50s of BRPF1/2/3=7.9/48/260 nM; Kds of BRPF1/2/3=40/210/940 nM) . It also has excellent selectivity over nonclass IV BRD proteins.

• Smiles :

  Cc1cc2cc(NS(=O)(=O)c3ccc(cc3)C#N)ccc2n(C)c1=O

• Molecular Formula :

  C18H15N3O3S

• Molecular Weight :

  353.39

• Shipping Conditions :

  Cool pack

• Storage Temperature :

  -20°C

• CAS Number :

  1884640-99-6