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Glipizide

CAT: 0931-T1603-02Size: 1 gDry Ice: NoHazardous: No
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CAT#:0931-T1603-02Size:1 g
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
29094-61-9
Target
Potassium Channel, ABC Transporter, PPAR
Related Pathways
Metabolism, DNA Damage/DNA Repair, Membrane transporter/Ion channel
Purity
0.9975
Bioactivity
Glipizide (CP 28720) is a short-acting, second-generation sulfonylurea with hypoglycemic activity.
Smiles
S(NC(NC1CCCCC1)=O)(=O)(=O)C2=CC=C(CCNC(=O)C=3C=NC(C)=CN3)C=C2
Molecular Formula
C21H27N5O4S
Molecular Weight
445.54
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

Chemical Information

Glipizide

Glipizide is an N-sulfonylurea that is glyburide in which the (5-chloro-2-methoxybenzoyl group is replaced by a (5-methylpyrazin-2-yl)carbonyl group. An oral hypoglycemic agent, it is used in the treatment of type 2 diabetes mellitus. It has a role as a hypoglycemic agent, an EC 2.7.1.33 (pantothenate kinase) inhibitor and an insulin secretagogue. It is a monocarboxylic acid amide, a member of pyrazines, an aromatic amide and a N-sulfonylurea.

CAS Number29094-61-9
PubChem CID3478
IUPAC NameN-[2-[4-(cyclohexylcarbamoylsulfamoyl)phenyl]ethyl]-5-methylpyrazine-2-carboxamide
Molecular FormulaC21H27N5O4S
Molecular Weight445.5
XLogP1.9
Topological Polar Surface Area139
Hydrogen Bond Donor Count3
Hydrogen Bond Acceptor Count6
Rotatable Bond Count7
Heavy Atom Count31
Formal Charge0
Complexity697
SMILES
CC1=CN=C(C=N1)C(=O)NCCC2=CC=C(C=C2)S(=O)(=O)NC(=O)NC3CCCCC3
InChI
InChI=1S/C21H27N5O4S/c1-15-13-24-19(14-23-15)20(27)22-12-11-16-7-9-18(10-8-16)31(29,30)26-21(28)25-17-5-3-2-4-6-17/h7-10,13-14,17H,2-6,11-12H2,1H3,(H,22,27)(H2,25,26,28)
InChIKey
ZJJXGWJIGJFDTL-UHFFFAOYSA-N
Chemical Structure
2D Structure
2D structure of Glipizide
CAS: 29094-61-9
CID: 3478
Formula: C21H27N5O4S
MW: 445.5
Interactive 3D Structure
Loading 3D structure...
View on PubChemRaw 3D data
Computed Properties
PropertyValue
Molecular Weight445.5
XLogP31.9
Hydrogen Bond Donor Count3
Hydrogen Bond Acceptor Count6
Rotatable Bond Count7
Exact Mass445.17837553
Monoisotopic Mass445.17837553
Topological Polar Surface Area139 Ų
Heavy Atom Count31
Formal Charge0
Complexity697
Isotope Atom Count0
Defined Atom Stereocenter Count0
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently-Bonded Unit Count1
Compound Is CanonicalizedYes

Alternative Products

CatalogName
A8438-1000Glipizide

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