Glipizide

CAT: 0804-HY-B0254-01Size: 100 mgDry Ice: NoHazardous: No
CAT#:0804-HY-B0254-01Size:100 mg
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Description
Glipizide (CP 2872; K 4024) a potent, orally active and sulfonylurea class anti-diabetic agent and can be used for type 2 diabetes mellitus research but not type 1. Glipizide acts by partially blocking ATP-sensitive potassium (KATP) channels among β cells of pancreatic islets of Langerhans[1][2].
CAS Number
[29094-61-9]
Product Name Alternative
CP 28720; K 4024
UNSPSC
12352005
Hazard Statement
H302, H315, H320, H335
Target
Potassium Channel
Type
Reference compound
Related Pathways
Membrane Transporter/Ion Channel
Applications
Metabolism-protein/nucleotide metabolism
Field of Research
Metabolic Disease; Cancer
Assay Protocol
https://www.medchemexpress.com/glipizide.html
Concentration
10mM
Purity
99.83
Solubility
DMSO : 50 mg/mL (ultrasonic) |H2O : < 0.1 mg/mL
Smiles
O=C(C1=NC=C(C)N=C1)NCCC2=CC=C(S(=O)(NC(NC3CCCCC3)=O)=O)C=C2
Molecular Formula
C21H27N5O4S
Molecular Weight
445.54
Precautions
H302, H315, H320, H335
References & Citations
[1]B J Zünkler, et al. Concentration-dependent effects of tolbutamide, meglitinide, glipizide, glibenclamide and diazoxide on ATP-regulated K+ currents in pancreatic B-cells. Naunyn Schmiedebergs Arch Pharmacol. 1988 Feb;337 (2) :225-30.|[2]Glipizide. From Wikipedia
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
Launched

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