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KGA-2727

CAT: 0931-T15656-01Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0931-T15656-01Size:1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
666842-36-0
Target
SGLT
Related Pathways
GPCR/G Protein
Purity
0.9895
Bioactivity
KGA-2727 is a potent and selective SGLT1 inhibitor, with Kis of 97.4 nM and 43.5 nM for human and rat SGLT1, respectively. The selectivity ratios (Ki for SGLT2/Ki for SGLT1) of KGA-2727 are 140 (human) and 390 (rat) . KGA-2727 for the treatment of diabete.
Smiles
CC(C)c1[nH]nc(O[C@@H]2O[C@H](CO)[C@@H](O)[C@H](O)[C@H]2O)c1Cc1ccc(OCCCNCCC(N)=O)cc1C
Molecular Formula
C26H40N4O8
Molecular Weight
536.62
Shipping Conditions
Ice Packs
Storage Temperature
-20°C