K-252a

• Target :

  PKC|||PKA|||Autophagy|||Serine/threonin kinase|||CaMK|||Apoptosis|||Antibiotic|||Trk receptor|||Tyrosinase

• Related Pathways :

  Chromatin/Epigenetic|||Autophagy|||Cell Cycle/Checkpoint|||Neuroscience|||Tyrosine Kinase/Adaptors|||Cytoskeletal Signaling|||Apoptosis|||Microbiology/Virology|||Metabolism|||Proteases/Proteasome

• Bioactivity :

  K-252a is a protein kinase inhibitor targeting serine-threonine, tyrosine, and CAM kinases. In vitro, it blocks NGF-induced TrkA signalling and neural differentiation, exhibiting antitumour, antibacterial, anti-inflammatory, and neuroprotective activities.

• Smiles :

  C[C@]12N3C=4C5=C(C6=C(C4C=7C3=CC=CC7)CNC6=O)C=8C(N5[C@](O1)(C[C@@]2(C(OC)=O)O)[H])=CC=CC8

• Molecular Formula :

  C27H21N3O5

• Molecular Weight :

  467.47

• Shipping Conditions :

  Cool pack

• Storage Temperature :

  -20°C

• CAS Number :

  99533-80-9