JHU-083 25mg

CAT: 0628-A18619-25Size: 25 mgDry Ice: NoHazardous: No

1 / 1

CAT#:0628-A18619-25Size:25 mg

Selected

24/48H Stock Items & 2 to 6 Weeks non Stock Items.

Quick Request Actions

CAS Number

1998725-11-3

Chemical Information

ethyl (2S)-2-(((2S)-2-amino-4-methylpentanoyl)amino)-6-diazo-5-oxohexanoate

JHU083 is an ethyl ester resulting from the formal condensation of the carboxy group of L-leucyl-6-diazo-5-oxo-L-norleucine with ethanol. It is a glutaminase inhibitor and a prodrug of 6-diazo-5-oxo-L-norleucine that exhibits antineoplastic activity. It has a role as an antineoplastic agent, a prodrug and an EC 3.5.1.2 (glutaminase) inhibitor. It is a secondary carboxamide, a ketone, an ethyl ester, a L-leucine derivative and a diazo compound.

CAS Number	1998725-11-3
PubChem CID	137283416
IUPAC Name	ethyl (2S)-2-[[(2S)-2-amino-4-methylpentanoyl]amino]-6-diazo-5-oxohexanoate
Molecular Formula	C14H24N4O4
Molecular Weight	312.36
XLogP	0.7
Topological Polar Surface Area	100
Hydrogen Bond Donor Count	2
Hydrogen Bond Acceptor Count	6
Rotatable Bond Count	11
Heavy Atom Count	22
Formal Charge	0
Complexity	444

SMILES

CCOC(=O)[C@H](CCC(=O)C=[N+]=[N-])NC(=O)[C@H](CC(C)C)N

InChI

InChI=1S/C14H24N4O4/c1-4-22-14(21)12(6-5-10(19)8-17-16)18-13(20)11(15)7-9(2)3/h8-9,11-12H,4-7,15H2,1-3H3,(H,18,20)/t11-,12-/m0/s1

InChIKey

YZRCHOFKIPHQBW-RYUDHWBXSA-N

Chemical Structure

2D Structure

CAS: 1998725-11-3

CID: 137283416

Formula: C14H24N4O4

MW: 312.36

Interactive 3D Structure

Loading 3D structure...

View on PubChem Raw 3D data

Computed Properties

Property	Value
Molecular Weight	312.36
XLogP3	0.7
Hydrogen Bond Donor Count	2
Hydrogen Bond Acceptor Count	6
Rotatable Bond Count	11
Exact Mass	312.17975526
Monoisotopic Mass	312.17975526
Topological Polar Surface Area	100 Å²
Heavy Atom Count	22
Formal Charge	0
Complexity	444
Isotope Atom Count	0
Defined Atom Stereocenter Count	2
Undefined Atom Stereocenter Count	0
Defined Bond Stereocenter Count	0
Undefined Bond Stereocenter Count	1
Covalently-Bonded Unit Count	1
Compound Is Canonicalized	Yes

Related Products

Catalog	Name
A18619-1	JHU-083 1mg
A18619-5	JHU-083 5mg
A18619-50	JHU-083 50mg
A18619-100	JHU-083 100mg
A18619-10	JHU-083 10mg
A15269-25	VAL-083 25mg
A15350-25	PhiKan 083 25mg
A21372-25	PhiKan 083 hydrochloride 25mg
A15269-1	VAL-083 1mg
A15350-500	PhiKan 083 500mg

Alternative Products

Catalog	Name
BA7770-5	JHU-083
463510	JHU 37152
MBS5819343	JHU 75528
MBS5812881	JHU-58

JHU-083 25mg

Chemical Information

Related Products

Alternative Products

Popular Products